Abstract In cryo-electron Functional Glassware microscopy (cryo-EM), sample preparation poses a critical bottleneck, particularly for rare or fragile macromolecular assemblies and those suffering from denaturation and particle orientation distribution issues related to air-water interface.In this study, we develop and characterize an immobilized an
Abstract Ligand-gated ion channels are formed by three to five subunits that control the opening of the pore in a cooperative fashion.We developed Slippery Elm a microfluidic chip-based technique for studying ion currents and fluorescence signals in either excised membrane patches or whole cells to measure activation and deactivation kinetics of th
The cationic complex in the title compound, [RuCl(C10H8N2)(C19H20N3O3P)]PF6·0.83CH3CN·0.17H2O, is a water-oxidation precatalyst functionalized for TiO2 attachment via terpyridine phosphonate.The The RuII atom in the complex has a distorted octahedral geometry due to the restricted bite angle [159.50 (18)°] of the terpyridyl lig
The enzyme glutamate-cysteine ligase modifier subunit (GCLM) serves as the initial rate-limiting factor in glutathione (GSH) synthesis.GSH is the preferred substrate for glutathione peroxidase 4 (GPX4), directly impacting its activity and stability.This study aims to elucidate the expression of GCLM and its correlation with the nuclear factor eryth
Research on the complicated and indeterminate autonomous transportation system (ATS) has drawn increased interest in order to better address issues associated with contemporary transportation development.Hoping to make transportation more sustainable, economical, safe, convenient, mask spoon and efficient, researchers try to address the expanding d